Little Boston, about a four-hour drive from New York City, is a popular day trip destination. The charm of the city lies in particular in the mixture of Europe and America in a small area. Boston is not a large city in terms of area, it can be explored relatively easily on foot.
The Big Apple is surrounded by many great cities and travel destinations, and so many make trips there from New York, and rightly so. We ourselves have made several days trips from New York. Either head north to Long Island, Boston, the Hamptons, or Niagara Falls.